Epigenetics and transgenerational inheritance in domesticated farm animals
نویسندگان
چکیده
منابع مشابه
Transgenerational Epigenetic Inheritance in Animals
with abiotic and biotic components of their surroundings. Whereas many and perhaps most of the encounters pass with transient changes at the molecular and metabolic levels, some have a profound impact on the phenotypic appearance of an organism and, more importantly, on the phenotypic appearance of their progeny. Since genetic changes are rare and random in nature, their influence on species or...
متن کاملTransgenerational Epigenetics
For this review of epigenetic transgenerational inheritance, it will be useful to provide some historical context. To that end, the initial experiments from the authors’ laboratory describing the phenomenon of epigenetic transgenerational inheritance will be outlined, and issues related to investigations in this field will be discussed using these studies as an example.1 Historically, the autho...
متن کاملTransgenerational Epigenetics
The regulation of gene expression through epigenetic modifications provides a dynamic route through which environmental experiences can lead to persistent changes in cellular phenotype. This plasticity plays an important role in mediating cellular differentiation and the potential stability of these modifications can lead to persistent and heritable variations in gene expression. Environmentall...
متن کاملEnvironmental signals and transgenerational epigenetics.
The ability of an environmental factor or toxicant to promote a phenotype or disease state not only in the individual exposed, but also in subsequent progeny for multiple generations, is termed transgenerational inheritance. The majority of environmental agents do not promote genetic mutations or alterations in DNA sequence, but do have the capacity to alter the epigenome. Although most environ...
متن کاملTransgenerational epigenetics and environmental justice
Human transmission to offspring and future generations of acquired epigenetic modifications has not been definitively established, although there are several environmental exposures with suggestive evidence. This article uses three examples of hazardous substances with greater exposures in vulnerable populations: pesticides, lead, and diesel exhaust. It then considers whether, if there were sci...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Animal Science and Biotechnology
سال: 2014
ISSN: 2049-1891
DOI: 10.1186/2049-1891-5-48